Endocrine Abstracts

The perchlorates block the enzyme NIS, inhibiting iodine accumulation in the thyroid and favour the elimination of intrathyroidal iodine unused for hormone synthesis. Their therapeutical utilisation actually is limited due to the toxicity. In the literature there are different opinions regarding the adverse effects (nephrotic syndrome, irreversible aplastic anemia etc.), but several authors sustain that these appear only after high doses, and after the development of therapeut...

Adrenocortical carcinoma is a rare disease, its estimated incidence being 1–2/million per year in general population. Age distribution shows two peaks: the first in early childhood (70% of patients having a benign evolution), and the second between 40 and 50 years of age (with a dismal prognosis).The 38-years-old male patient (C A) hospitalized in our Clinic in September 2008 presented hypertension (to 250/150 mmHg) for about 3 months, lumbar pain w...